苏氨酸 (THR)
L-苏氨酸(L-Threonine)
CAS: 72-19-5;6028-28-0
化学式: C4H9NO3
性质
白色结晶或结晶性粉末，无臭，味稍甜。易溶于水，难溶于乙醇等有机溶剂。化学性能较稳定。
制法
以巴豆酸或甘氨酸为原料制得，或者使用葡萄糖或淀粉。发酵过程需要大肠杆菌、黄色短杆菌、谷氨酸杆菌或钝齿棒杆菌等菌种。
用途
苏氨酸是一种必需的氨基酸，主要用于猪饲料和家禽饲料的强化剂，尤其是小麦、大麦等谷物为主的饲料。芬氨酸则是一种必需的氨基酸，常作为营养强化剂添加到饲料中。苏氨酸是猪饲料的第二限制氨基酸，而家禽饲料的第三限制氨基酸。
安全性
- 成人一次滴注22. 5g时可引起发烧，头痛等不良反应。
- 遮光，密闭保存。
| 中文名 | L-苏氨酸 |
| 英文名 | L-Threonine |
| 别名 | 苏氨酸 L-苏氨酸 饲料级苏氨酸 L-羟基丁氨酸 L-苏氨酸标准品 苏氨酸 (THR) L-苏氨酸(饲料级) α-氨基-β-羟基丁酸 苏氨酸溶液 (THR) 2S,3R)-2-氨基-3-羟基丁酸 (2S,3R)-2-氨基-3-羟基丁酸 |
| 英文别名 | Thr L-THR H-THR-OH H-Thr-OH Threonine H-L-THR-OH L-Threonin L-Threonine L-THREONINE L(-)-THREONINE H-THR-OH-THREONINE (2S,3R)-(-)-Threonine L-Threonine, USP Grade L-Threonine, allo-Free 2-Amino-3-hydroxybutanoic acid L-2-Amino-3-hydroxybutyric acid L-2-AMINO-3-HYDROXYBUTYRIC ACID L-2-AMINO-3-HYDROXYBUTANOIC ACID (2S,3R)-2-Amino-3-hydroxybutyric acid 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde semicarbazone |
| CAS | 72-19-5 6028-28-0 |
| EINECS | 200-774-1 |
| 化学式 | C4H9NO3 |
| 分子量 | 119.12 |
| InChI | InChI=1/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2?,3-/m0/s1 |
| InChIKey | AYFVYJQAPQTCCC-GBXIJSLDSA-N |
| 密度 | 1.3126 (rough estimate) |
| 熔点 | 256 °C (dec.) (lit.) |
| 沸点 | 222.38°C (rough estimate) |
| 比旋光度 | -28.4 º (c=6, H2O) |
| 闪点 | 162.936°C |
| 水溶性 | 90 g/L (20 ºC) |
| 蒸汽压 | 0mmHg at 25°C |
| JECFA Number | 2119 |
| 溶解度 | H2O: 50 mg/mL |
| 折射率 | -28 ° (C=6, H2O) |
| 酸度系数 | 2.09(at 25℃) |
| PH值 | 5-6 (100g/l, H2O, 20℃) |
| 存储条件 | 2-8°C |
| 稳定性 | 稳定。与强氧化剂不相容。 |
| 外观 | 粉末 |
| 颜色 | Yellow |
| Merck | 14,9380 |
| BRN | 1721646 |
| 物化性质 | 白色斜方晶系或结晶性粉末。无臭，味微甜 |
| MDL号 | MFCD00064270 |
| 危险品标志 | Xi - 刺激性物品 |
| 风险术语 | 36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
| 安全术语 | S24/25 - 避免与皮肤和眼睛接触。 S37/39 - 戴适当的手套和护目镜或面具。 S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 |
| WGK Germany | 3 |
| RTECS | XO8590000 |
| TSCA | Yes |
| 海关编号 | 29225000 |
| Hazard Note | Irritant |
| 上游原料 | 蛋白质 酪蛋白 酰化氨基酸水解酶 甘氨酸铜 丝心蛋白 |
| 下游产品 | 盐酸赖氨酸 L-2-氨基-3-羟基丁酸-3-磷酸酯 |
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Xinru Xu, Mingguang Yu, Junaid Raza, Huanlu Song, Lin Gong, Wenqing Pan, Study of the mechanism of flavor compounds formed via taste-active peptides in bovine bone protein extract, LWT, Volume 137, 2021, 110371, ISSN 0023-6438, https://doi.org/10.1016/j.lw 12. Zhongqian Song, Fengyu Quan, Yuanhong Xu, Mengli Liu, Liang Cui, Jingquan Liu, Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione, Carbon, Volume 10 13. Zhao, Zheng, et al. "Cholinium amino acids-glycerol mixtures: New class of solvents for pretreating wheat straw to facilitate enzymatic hydrolysis." Bioresource technology 245 (2017): 625-632.https://doi.org/10.1016/j.biortech.2017.08.209 14. [IF=9.594] Zhongqian Song et al."Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione."Carbon. 2016 Aug;104:169 15. 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[IF=4.952] Xinru Xu et al."Study of the mechanism of flavor compounds formed via taste-active peptides in bovine bone protein extract."Lwt Food Sci Technol. 2021 Feb;137:110371 24. [IF=4.952] Huan Zhang et al."Label-free quantification proteomics reveals the active peptides from protein degradation during anaerobic fermentation of tea."Lwt Food Sci Technol. 2021 Oct;150:111950 25. [IF=4.821] Yixin Nie et al."Nitrogen-rich quantum dots-based fluorescence molecularly imprinted paper strip for p-nitroaniline detection."Microchem J. 2019 Jul;148:162 26. [IF=4.821] Peng Wan et al."Analysis of aroma-active compounds in bighead carp head soup and their influence on umami of a model soup."Microchem J. 2021 Sep;168:106436 27. [IF=4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning."J Food Compos Anal. 2020 May;88:103460 28. [IF=4.418] Yuan Li et al."Deciphering the Mechanism of the Anti-Hypertensive Effect of Isorhynchophylline by Targeting Neurotransmitters Metabolism of Hypothalamus in Spontaneously Hypertensive Rats."Acs Chem Neurosci. 2020;11(11):1563–1572 29. [IF=4.411] Mengxia Tan et al."Quality Evaluation of Ophiopogonis Radix from Two Different Producing Areas."Molecules. 2019 Jan;24(18):3220 30. [IF=4.411] Shengxin Yin et al."Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot."Molecules. 2021 Jan;26(7):1864 31. [IF=4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10 32. [IF=4.35] Xiaomei Dai et al."1-Methylcyclopropene Preserves the Quality of Chive (Allium schoenoprasum L.) by Enhancing Its Antioxidant Capacities and Organosulfur Profile during Storage."Foods. 2021 Aug;10(8):1792 33. [IF=4.142] Qu Fei et al."Ratiometric detection of alkaline phosphatase based on aggregation-induced emission enhancement."Anal Bioanal Chem. 2019 Nov;411(28):7431-7440 34. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4 35. [IF=4.142] Li Cong et al."A fluorescence strategy for monitoring α-glucosidase activity and screening its inhibitors from Chinese herbal medicines based on Cu nanoclusters with aggregation-induced emission."Anal Bioanal Chem. 2021 Apr;413(9):2553-2563 36. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697 37. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC–MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243 38. [IF=3.366] Qu Fei et al."Fluorescent Detection of 2,4-Dichlorophenoxyacetic Acid in Food Samples Based on Covalent Organic Frameworks and MnO2 Nanosheets."Food Anal Method. 2020 Oct;13(10):1842-1851 39. [IF=3.361] Ruixue Yu et al."Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats."Rsc Adv. 2019 Jul;9(40):23276-23288 40. [IF=2.097] Ke Jing et al."Isocratic micellar liquid chromatography using mixed anionic and non-ionic surfactants as mobile phase additives for separation of 17 free amino acids."Chem Pap. 2019 Oct;73(10):2417-2426 41. 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苏氨酸 (THR) - 性质
可信数据
白色结晶或结晶性粉末，无臭，味稍甜。易溶于水，难溶于乙醇等有机溶剂。化学性能较稳定。
最后更新：2024-01-02 23:10:35
苏氨酸 (THR) - 制法
可信数据
以巴豆酸或甘氨酸为原料制得，或者使用葡萄糖或淀粉。发酵过程需要大肠杆菌、黄色短杆菌、谷氨酸杆菌或钝齿棒杆菌等菌种。
最后更新：2025-06-10 22:55:16
苏氨酸 (THR) - 用途
可信数据
苏氨酸是一种必需的氨基酸，主要用于猪饲料和家禽饲料的强化剂，尤其是小麦、大麦等谷物为主的饲料。芬氨酸则是一种必需的氨基酸，常作为营养强化剂添加到饲料中。苏氨酸是猪饲料的第二限制氨基酸，而家禽饲料的第三限制氨基酸。
最后更新：2025-08-19 16:24:40
苏氨酸 (THR) - 安全性
可信数据
- 成人一次滴注22. 5g时可引起发烧，头痛等不良反应。
- 遮光，密闭保存。
最后更新：2022-01-01 11:10:22
苏氨酸 (THR) - 简介
L-苏氨酸是一种天然氨基酸，也是人体蛋白质的组成部分之一。它是一种无色结晶粉末，可溶于水。
L-苏氨酸的制法通常是通过微生物发酵或化学合成得到的。微生物发酵法主要依靠某些细菌或酵母的代谢能力，通过对合适的底物进行培养和提取来产生L-苏氨酸。化学合成法则是通过化学方法合成L-苏氨酸。这些方法都可以得到高纯度的L-苏氨酸。
L-苏氨酸的制法通常是通过微生物发酵或化学合成得到的。微生物发酵法主要依靠某些细菌或酵母的代谢能力，通过对合适的底物进行培养和提取来产生L-苏氨酸。化学合成法则是通过化学方法合成L-苏氨酸。这些方法都可以得到高纯度的L-苏氨酸。
最后更新：2024-04-09 18:58:34
供应商列表
主打产品现货供应
产品名: L-苏氨酸 去供应商网站查看 询盘CAS: 72-19-5
产地: 上海
包装: 500g,100g,20g,5g,100g,500g,25g,2.5kg,25g,1kg,100g,5kg,500g,1ml,25g
规格: L675531
价格: 8432,2108,612,188,96,296,39,1100,29,233,42,899,140,340,615
库存: 现货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2881510266
微信: 19863730987/17821173903
现货供应
产品名: L-赖氨酸杂质3（赖氨酸EP杂质C） 去供应商网站查看 询盘CAS: 72-19-5
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
手机: 18186386804
电子邮件: 2885409035@qq.com
QQ: 2885409035
微信: 18186386804
产品描述: 91203L
提供多种规格现货供应
产品名: 水中L-苏氨酸标准溶液1000μg/ml 去供应商网站查看 询盘CAS: 72-19-5
产地: 北京
包装: 1ml/瓶,5*1ml/瓶
规格: BY113440
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 18101056239(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 18101056239
产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
主打产品现货供应
产品名: L-苏氨酸 去供应商网站查看 询盘CAS: 72-19-5
产地: 上海
包装: 500g,100g,20g,5g,100g,500g,25g,2.5kg,25g,1kg,100g,5kg,500g,1ml,25g
规格: L675531
价格: 8432,2108,612,188,96,296,39,1100,29,233,42,899,140,340,615
库存: 现货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2881510266
微信: 19863730987/17821173903
现货供应
产品名: L-赖氨酸杂质3（赖氨酸EP杂质C） 去供应商网站查看 询盘CAS: 72-19-5
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
手机: 18186386804
电子邮件: 2885409035@qq.com
QQ: 2885409035
微信: 18186386804
产品描述: 91203L
提供多种规格现货供应
产品名: 水中L-苏氨酸标准溶液1000μg/ml 去供应商网站查看 询盘CAS: 72-19-5
产地: 北京
包装: 1ml/瓶,5*1ml/瓶
规格: BY113440
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 18101056239(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 18101056239
产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
苏氨酸 (THR)的上游原料
苏氨酸 (THR)的下游产品
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